EMD-16023

Helical reconstruction
1.99 Å
EMD-16023
3D View Gallery
Deposition: 27/10/2022
Map released: 18/01/2023
Last modified: 05/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16023

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8bg0 summary report (pdf.gz) Map-8bg0 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40

EMD-16023

Helical reconstruction
1.99 Å
EMD-16023
3D View Gallery
Deposition: 27/10/2022
Map released: 18/01/2023
Last modified: 05/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Amyloid-beta filaments extracted from the human brain with Arctic mutation (E693G) of Alzheimer's disease
Fitted models: 8bg0

Deposition Authors: Yang Y , Zhang WJ, Murzin AG, Schweighauser M, Huang M , Lovestam SKA, Peak-Chew SY, Macdonald J, Lavenir I, Ghetti B, Graff C , Kumar A, Nordber A, Goedert M, Scheres SHW
Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
Yang Y , Zhang W , Murzin AG, Schweighauser M, Huang M , Lovestam S, Peak-Chew SY, Saito T , Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C , Kumar A, Nordberg A, Goedert M, Scheres SHW
(2023) Acta Neuropathol , 145 , 325 - 333
PUBMED: 36611124
DOI: doi:10.1007/s00401-022-02533-1
ISSN: 1432-0533