Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-15905
Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
EMD-15905
Single-particle3.0 Å
Deposition: 03/10/2022Map released: 25/01/2023
Last modified: 12/03/2025
Sample Organism:
Escherichia coli K-12,
Escherichia coli BW25113,
Myxococcus fulvus
Sample: Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
Fitted models: 8b7y
Deposition Authors: Koller TO
,
Graf M,
Wilson DN
Sample: Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
Fitted models: 8b7y
Deposition Authors: Koller TO
,
Graf M,
Wilson DN
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
Koller TO ,
Scheid U,
Kosel T,
Herrmann J ,
Krug D ,
Boshoff HIM ,
Beckert B,
Evans JC ,
Schlemmer J,
Sloan B,
Weiner DM,
Via LE,
Moosa A ,
Ioerger TR,
Graf M,
Zinshteyn B,
Abdelshahid M,
Nguyen F,
Arenz S,
Gille F,
Siebke M,
Seedorf T,
Plettenburg O ,
Green R,
Warnke AL ,
Ullrich J,
Warrass R,
Barry 3rd CE ,
Warner DF ,
Mizrahi V ,
Kirschning A ,
Wilson DN ,
Muller R
(2023) J Am Chem Soc , 145 , 851 - 863
,
Scheid U,
Kosel T,
Herrmann J ,
Krug D ,
Boshoff HIM ,
Beckert B,
Evans JC ,
Schlemmer J,
Sloan B,
Weiner DM,
Via LE,
Moosa A ,
Ioerger TR,
Graf M,
Zinshteyn B,
Abdelshahid M,
Nguyen F,
Arenz S,
Gille F,
Siebke M,
Seedorf T,
Plettenburg O ,
Green R,
Warnke AL ,
Ullrich J,
Warrass R,
Barry 3rd CE ,
Warner DF ,
Mizrahi V ,
Kirschning A ,
Wilson DN ,
Muller R
(2023) J Am Chem Soc , 145 , 851 - 863
Grant Support:
- German Research Foundation (DFG): WI3285/6-1 (Germany)