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EMD-15772
Paired helical tau filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | PHF Tau
EMD-15772
Helical reconstruction3.1 Å
Deposition: 06/09/2022Map released: 24/05/2023
Last modified: 24/07/2024
Sample Organism:
Homo sapiens
Sample: Paired helical tau filament in soluble high-molecular weight aggregate fractions extracted from the Alzheimer's disease brain
Fitted models: 8azu
Deposition Authors: Yang Y
,
Stern MA,
Meunier LA,
Liu W,
Cai YQ,
Ericsson M,
Liu L,
Selkoe JD,
Goedert M,
Scheres HWS
Sample: Paired helical tau filament in soluble high-molecular weight aggregate fractions extracted from the Alzheimer's disease brain
Fitted models: 8azu
Deposition Authors: Yang Y
,
Stern MA,
Meunier LA,
Liu W,
Cai YQ,
Ericsson M,
Liu L,
Selkoe JD,
Goedert M,
Scheres HWS
Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Stern AM,
Yang Y ,
Jin S,
Yamashita K ,
Meunier AL,
Liu W,
Cai Y ,
Ericsson M,
Liu L,
Goedert M,
Scheres SHW,
Selkoe DJ
(2023) Neuron , 111 , 2012
,
Jin S,
Yamashita K ,
Meunier AL,
Liu W,
Cai Y ,
Ericsson M,
Liu L,
Goedert M,
Scheres SHW,
Selkoe DJ
(2023) Neuron , 111 , 2012
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/25 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)