Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-15712

Single-particle
1.96 Å
EMD-15712
3D View Gallery
Deposition: 02/09/2022
Map released: 01/03/2023
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15712
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8aye summary report (pdf.gz) Map and 8aye FULL report (pdf.gz)
EMICSS annotations (xml)

E. coli 70S ribosome bound to thermorubin and fMet-tRNA

EMD-15712

Single-particle
1.96 Å
EMD-15712
3D View Gallery
Deposition: 02/09/2022
Map released: 01/03/2023
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: E. coli 70S ribosome bound to thermorubin and fMet-tRNA
Fitted models: 8aye

Deposition Authors: Sanyal S , Parajuli NP , Emmerich AG
Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.
Parajuli NP , Emmerich A , Mandava CS, Pavlov MY, Sanyal S
(2023) Nat Commun , 14 , 918 - 918
PUBMED: 36806263
DOI: doi:10.1038/s41467-023-36528-7
ISSN: 2041-1723