EMD-15697
Cryo-EM structure of shCas12k-sgRNA-dsDNA ternary complex (type V-K CRISPR-associated transposon)
EMD-15697
Single-particle2.96 Å
Deposition: 31/08/2022Map released: 10/04/2024
Last modified: 03/07/2024
Sample Organism:
Scytonema hofmannii
Sample: Ternary complex of ShCas12k bound to sgRNA and dsDNA.
Fitted models: 8axa
Deposition Authors: Tenjo-Castano F, Sofos N
,
Stella S,
Fuglsang A ,
Pape T ,
Mesa P ,
Stutzke LS,
Temperini P,
Montoya G
Sample: Ternary complex of ShCas12k bound to sgRNA and dsDNA.
Fitted models: 8axa
Deposition Authors: Tenjo-Castano F, Sofos N
,
Stella S,
Fuglsang A ,
Pape T ,
Mesa P ,
Stutzke LS,
Temperini P,
Montoya G
Conformational landscape of the type V-K CRISPR-associated transposon integration assembly.
Tenjo-Castano F,
Sofos N ,
Stutzke LS,
Temperini P,
Fuglsang A ,
Pape T ,
Mesa P ,
Montoya G
(2024) Mol Cell , 84 , 2353 - 2367.e5
,
Stutzke LS,
Temperini P,
Fuglsang A ,
Pape T ,
Mesa P ,
Montoya G
(2024) Mol Cell , 84 , 2353 - 2367.e5
Grant Support:
- Novo Nordisk Foundation: NNF0024386 (Denmark)
- Novo Nordisk Foundation: NNF14CC0001 (Denmark)
- Novo Nordisk Foundation: NNF17SA0030214 (Denmark)
- Novo Nordisk Foundation: NNF18OC0055061 (Denmark)