EMD-15689

Single-particle
3.01 Å
EMD-15689
3D View Gallery
Deposition: 29/08/2022
Map released: 06/03/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15689

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8aw2 summary report (pdf.gz) Map-8aw2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Mouse serotonin 5-HT3A receptor in complex with vortioxetine

EMD-15689

Single-particle
3.01 Å
EMD-15689
3D View Gallery
Deposition: 29/08/2022
Map released: 06/03/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse serotonin 5-HT3A receptor in complex with vortioxetine
Fitted models: 8aw2

Deposition Authors: Lopez-Sanchez U , Nury H
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Lopez-Sanchez U , Munro LJ, Ladefoged LK , Pedersen AJ, Brun CC, Lyngby SM, Baud D, Juillan-Binard C, Pedersen MG, Lummis SCR, Bang-Andersen B , Schiott B , Chipot C, Schoehn G , Neyton J, Dehez F , Nury H , Kristensen AS
(2024) Nat Struct Mol Biol , 31 , 1232 - 1242
PUBMED: 38698207
DOI: doi:10.1038/s41594-024-01282-x
ISSN: 1545-9985
Grant Support: