EMD-15681
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model)
EMD-15681
Single-particle6.45 Å
Deposition: 26/08/2022Map released: 05/04/2023
Last modified: 20/11/2024
Sample Organism:
Homo sapiens
Sample: Human leptin in complex with the human LEP-R ectodomain C-terminally fused to a trimeric GCN4 isoleucine zipper tag
Fitted models: 8avf
Deposition Authors: Verstraete K
,
Savvides SN ,
Verschueren KG,
Tsirigotaki A
Sample: Human leptin in complex with the human LEP-R ectodomain C-terminally fused to a trimeric GCN4 isoleucine zipper tag
Fitted models: 8avf
Deposition Authors: Verstraete K
,
Savvides SN ,
Verschueren KG,
Tsirigotaki A
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A,
Dansercoer A,
Verschueren KHG,
Markovic I ,
Pollmann C ,
Hafer M,
Felix J ,
Birck C ,
Van Putte W ,
Catteeuw D,
Tavernier J ,
Fernando Bazan J,
Piehler J ,
Savvides SN ,
Verstraete K
(2023) Nat Struct Mol Biol , 30 , 551 - 563
,
Pollmann C ,
Hafer M,
Felix J ,
Birck C ,
Van Putte W ,
Catteeuw D,
Tavernier J ,
Fernando Bazan J,
Piehler J ,
Savvides SN ,
Verstraete K
(2023) Nat Struct Mol Biol , 30 , 551 - 563
Grant Support:
- Research Foundation - Flanders (FWO): G0G0619N (Belgium)