EMD-15233

Single-particle
4.0 Å
EMD-15233
3D View Gallery
Deposition: 23/06/2022
Map released: 13/07/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15233

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8a8m summary report (pdf.gz) Map-8a8m FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the MAPK p38alpha in complex with its activating MAP2K MKK6

EMD-15233

Single-particle
4.0 Å
EMD-15233
3D View Gallery
Deposition: 23/06/2022
Map released: 13/07/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex between the MAP2K MKK6 and its substrate MAPK p38alpha
Fitted models: 8a8m

Deposition Authors: Bowler MW , Juyoux P , Pellegrini E
Architecture of the MKK6-p38 alpha complex defines the basis of MAPK specificity and activation.
Juyoux P , Galdadas I , Gobbo D , von Velsen J , Pelosse M , Tully M , Vadas O , Gervasio FL , Pellegrini E , Bowler MW
(2023) Science , 381 , 1217 - 1225
PUBMED: 37708276
DOI: doi:10.1126/science.add7859
ISSN: 1095-9203
ASTM: SCIEAS
Grant Support: