Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-15043

Helical reconstruction
2.6 Å
EMD-15043
3D View Gallery
Deposition: 26/05/2022
Map released: 18/01/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-15043
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8a00 summary report (pdf.gz) Map and 8a00 FULL report (pdf.gz)
EMICSS annotations (xml)

Infectious mouse-adapted ME7 scrapie prion fibril purified from terminally-infected mouse brains

EMD-15043

Helical reconstruction
2.6 Å
EMD-15043
3D View Gallery
Deposition: 26/05/2022
Map released: 18/01/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: amyloid fibril of prion protein
Fitted models: 8a00

Deposition Authors: Manka SW , Wenborn A, Betts J, Joiner S, Saibil HR , Collinge J , Wadsworth JDF
A structural basis for prion strain diversity.
Manka SW , Wenborn A, Betts J, Joiner S, Saibil HR , Collinge J , Wadsworth JDF
(2023) Nat Chem Biol , 19 , 607 - 613
PUBMED: 36646960
DOI: doi:10.1038/s41589-022-01229-7
ISSN: 1552-4469