EMD-14995

Single-particle
2.8 Å
EMD-14995
3D View Gallery
Deposition: 19/05/2022
Map released: 31/05/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14995

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7zwa summary report (pdf.gz) Map-7zwa FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of Ku heterodimer bound to DNA and PAXX

EMD-14995

Single-particle
2.8 Å
EMD-14995
3D View Gallery
Deposition: 19/05/2022
Map released: 31/05/2023
Last modified: 24/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ku70/80 heterodimer bound to DNA and PAXX
Fitted models: 7zwa

Deposition Authors: Hardwick SW , Kefala-Stavridi A, Chirgadze DY , Blundell TL , Chaplin AK
PAXX binding to the NHEJ machinery explains functional redundancy with XLF.
Seif-El-Dahan M, Kefala-Stavridi A, Frit P , Hardwick SW , Chirgadze DY , Maia De Oliviera T , Britton S , Barboule N, Bossaert M , Pandurangan AP , Meek K , Blundell TL , Ropars V, Calsou P , Charbonnier JB , Chaplin AK
(2023) Sci Adv , 9 , eadg2834 - eadg2834
PUBMED: 37256950
DOI: doi:10.1126/sciadv.adg2834
ISSN: 2375-2548
Grant Support: