Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-14986

Single-particle
2.74 Å
EMD-14986
3D View Gallery
Deposition: 17/05/2022
Map released: 24/05/2023
Last modified: 06/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14986
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7zvt summary report (pdf.gz) Map and 7zvt FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of Ku heterodimer bound to DNA

EMD-14986

Single-particle
2.74 Å
EMD-14986
3D View Gallery
Deposition: 17/05/2022
Map released: 24/05/2023
Last modified: 06/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ku70/80 heterodimer bound to DNA
Fitted models: 7zvt

Deposition Authors: Hardwick SW, Kefala-Stavridi A, Chirgadze DY, Blundell TL, Chaplin AK
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J , Rak A , Legrand P , Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E , Britton S , Calsou P, Blundell TL, Varela PF , Chaplin AK , Charbonnier JB
(2023) Nucleic Acids Res , 51 , 11732 - 11747
PUBMED: 37870477
DOI: doi:10.1093/nar/gkad863
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: