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EMD-14955
Cryo-EM structure of Ku 70/80 bound to inositol hexakisphosphate
EMD-14955
Single-particle3.5 Å
Deposition: 09/05/2022Map released: 17/05/2023
Last modified: 06/12/2023
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of Ku 70/80 bound to inositol hexakisphosphate
Fitted models: 7zt6
Deposition Authors: Kefala Stavridi A, Chaplin AK
,
Blundell TL
Sample: Cryo-EM structure of Ku 70/80 bound to inositol hexakisphosphate
Fitted models: 7zt6
Deposition Authors: Kefala Stavridi A, Chaplin AK
,
Blundell TL
Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A,
Gontier A,
Morin V,
Frit P,
Ropars V,
Barboule N,
Racca C,
Jonchhe S,
Morten MJ,
Andreani J
,
Rak A
,
Legrand P
,
Bourand-Plantefol A,
Hardwick SW,
Chirgadze DY,
Davey P,
De Oliveira TM,
Rothenberg E
,
Britton S
,
Calsou P,
Blundell TL,
Varela PF
,
Chaplin AK
,
Charbonnier JB
(2023) Nucleic Acids Res , 51 , 11732 - 11747
,
Rak A
,
Legrand P
,
Bourand-Plantefol A,
Hardwick SW,
Chirgadze DY,
Davey P,
De Oliveira TM,
Rothenberg E
,
Britton S
,
Calsou P,
Blundell TL,
Varela PF
,
Chaplin AK
,
Charbonnier JB
(2023) Nucleic Acids Res , 51 , 11732 - 11747
Grant Support:
- Wellcome Trust: 200814/Z/16/Z (United Kingdom)
