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EMD-14947
cryo-EM structure of D614 spike in complex with de novo designed binder, full and local maps(addition)
EMD-14947
Single-particle2.63 Å
Deposition: 08/05/2022Map released: 01/03/2023
Last modified: 13/11/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Drosophila melanogaster
Sample: D614G spike in complex with de novo designed binder
Fitted models: 7zss
Deposition Authors: Pablo G, Sarah W, Alexandra VH, Anthony M, Andreas S, Zander H, Dongchun N, Shuguang T, Freyr S, Casper G, Priscilla T, Alexandra T, Stephane R, Sandrine G, Jane M, Aaron P, Zepeng X, Yan C, Pu H, George G, Elisa O, Beat F, Didier T, Henning S, Michael B, Bruno EC
Sample: D614G spike in complex with de novo designed binder
Fitted models: 7zss
Deposition Authors: Pablo G, Sarah W, Alexandra VH, Anthony M, Andreas S, Zander H, Dongchun N, Shuguang T, Freyr S, Casper G, Priscilla T, Alexandra T, Stephane R, Sandrine G, Jane M, Aaron P, Zepeng X, Yan C, Pu H, George G, Elisa O, Beat F, Didier T, Henning S, Michael B, Bruno EC
De novo design of protein interactions with learned surface fingerprints.
Gainza P 
,
Wehrle S,
Van Hall-Beauvais A,
Marchand A ,
Scheck A ,
Harteveld Z,
Buckley S ,
Ni D ,
Tan S ,
Sverrisson F,
Goverde C ,
Turelli P ,
Raclot C ,
Teslenko A ,
Pacesa M ,
Rosset S,
Georgeon S,
Marsden J,
Petruzzella A ,
Liu K,
Xu Z,
Chai Y,
Han P ,
Gao GF ,
Oricchio E ,
Fierz B ,
Trono D ,
Stahlberg H ,
Bronstein M ,
Correia BE
(2023) Nature , 617 , 176 - 184
,
Wehrle S,
Van Hall-Beauvais A,
Marchand A ,
Scheck A ,
Harteveld Z,
Buckley S ,
Ni D ,
Tan S ,
Sverrisson F,
Goverde C ,
Turelli P ,
Raclot C ,
Teslenko A ,
Pacesa M ,
Rosset S,
Georgeon S,
Marsden J,
Petruzzella A ,
Liu K,
Xu Z,
Chai Y,
Han P ,
Gao GF ,
Oricchio E ,
Fierz B ,
Trono D ,
Stahlberg H ,
Bronstein M ,
Correia BE
(2023) Nature , 617 , 176 - 184
Grant Support:
- European Research Council (ERC): European Research Council (starting grant no. 716058) (European Union)
- Swiss National Science Foundation: NCCR transcure 185544 (Switzerland)
- Swiss National Science Foundation: 310030_188744 (Switzerland)
- Swiss National Science Foundation: NCCR Molecular Systems Engineering (Switzerland)
- Swiss National Science Foundation: NCCR Chemical Biology (Switzerland)