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EMD-14922
cryo-EM structure of omicron spike in complex with de novo designed binder, full map
EMD-14922
Single-particle2.8 Å
Deposition: 05/05/2022Map released: 08/03/2023
Last modified: 13/11/2024
Sample Organism:
Drosophila melanogaster,
Severe acute respiratory syndrome coronavirus 2,
Tequatrovirus T4
Sample: omicron spike in complex with de novo designed binder, full map
Fitted models: 7zrv
Deposition Authors: Pablo G, Sarah W, Alexandra VH, Anthony M, Andreas S, Zander H, Dongchun N, Shuguang T, Freyr S, Casper G, Priscilla T, Alexandra T, Stephane R, Sandrine G, Jane M, Aaron P, Zepeng X, Yan C, Pu H, George G, Elisa O, Beat F, Didier T, Henning S, Michael B, Bruno EC
Sample: omicron spike in complex with de novo designed binder, full map
Fitted models: 7zrv
Deposition Authors: Pablo G, Sarah W, Alexandra VH, Anthony M, Andreas S, Zander H, Dongchun N, Shuguang T, Freyr S, Casper G, Priscilla T, Alexandra T, Stephane R, Sandrine G, Jane M, Aaron P, Zepeng X, Yan C, Pu H, George G, Elisa O, Beat F, Didier T, Henning S, Michael B, Bruno EC
De novo design of protein interactions with learned surface fingerprints.
Gainza P 
,
Wehrle S,
Van Hall-Beauvais A,
Marchand A ,
Scheck A ,
Harteveld Z,
Buckley S ,
Ni D ,
Tan S ,
Sverrisson F,
Goverde C ,
Turelli P ,
Raclot C ,
Teslenko A ,
Pacesa M ,
Rosset S,
Georgeon S,
Marsden J,
Petruzzella A ,
Liu K,
Xu Z,
Chai Y,
Han P ,
Gao GF ,
Oricchio E ,
Fierz B ,
Trono D ,
Stahlberg H ,
Bronstein M ,
Correia BE
(2023) Nature , 617 , 176 - 184
,
Wehrle S,
Van Hall-Beauvais A,
Marchand A ,
Scheck A ,
Harteveld Z,
Buckley S ,
Ni D ,
Tan S ,
Sverrisson F,
Goverde C ,
Turelli P ,
Raclot C ,
Teslenko A ,
Pacesa M ,
Rosset S,
Georgeon S,
Marsden J,
Petruzzella A ,
Liu K,
Xu Z,
Chai Y,
Han P ,
Gao GF ,
Oricchio E ,
Fierz B ,
Trono D ,
Stahlberg H ,
Bronstein M ,
Correia BE
(2023) Nature , 617 , 176 - 184
Grant Support:
- European Research Council (ERC): European Research Council (starting grant no. 716058) (European Union)
- Swiss National Science Foundation: NCCR transcure 185544 (Switzerland)
- Swiss National Science Foundation: 310030_188744 (Switzerland)
- Swiss National Science Foundation: NCCR Molecular Systems Engineering (Switzerland)
- Swiss National Science Foundation: NCCR Chemical Biology (Switzerland)