Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-14802
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD
EMD-14802
Single-particle3.78 Å
Deposition: 20/04/2022Map released: 09/11/2022
Last modified: 24/07/2024
Sample Organism:
Murid betaherpesvirus 8,
Homo sapiens,
Rattus norvegicus
Sample: Ternary complex of RCMV-E E27 with human DDB1 (deltaBPB) and rat STAT2
Fitted models: 7zn7
Deposition Authors: Lauer S, Spahn CMT, Schwefel D
Sample: Ternary complex of RCMV-E E27 with human DDB1 (deltaBPB) and rat STAT2
Fitted models: 7zn7
Deposition Authors: Lauer S, Spahn CMT, Schwefel D
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Le-Trilling VTK ,
Banchenko S ,
Paydar D,
Leipe PM,
Binting L,
Lauer S,
Graziadei A ,
Klingen R ,
Gotthold C,
Burger J ,
Bracht T ,
Sitek B,
Jan Lebbink R ,
Malyshkina A ,
Mielke T ,
Rappsilber J ,
Spahn CM,
Voigt S ,
Trilling M ,
Schwefel D
(2023) EMBO J , 42 , e112351 - e112351
,
Banchenko S ,
Paydar D,
Leipe PM,
Binting L,
Lauer S,
Graziadei A ,
Klingen R ,
Gotthold C,
Burger J ,
Bracht T ,
Sitek B,
Jan Lebbink R ,
Malyshkina A ,
Mielke T ,
Rappsilber J ,
Spahn CM,
Voigt S ,
Trilling M ,
Schwefel D
(2023) EMBO J , 42 , e112351 - e112351
Grant Support:
- German Research Foundation (DFG): SCHW 1851/1-1 (Germany)