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EMD-14717
SARS CoV Spike protein, Closed C3 conformation
EMD-14717
Single-particle2.48 Å
Deposition: 05/04/2022Map released: 15/02/2023
Last modified: 23/10/2024
Sample Organism:
Severe acute respiratory syndrome-related coronavirus,
Enterobacteria phage T4
Sample: SARS CoV Spike protein, Closed conformation, C3 symmetry
Fitted models: 7zh1
Deposition Authors: Toelzer C
,
Gupta K
,
Yadav SKN
,
Buzas D
,
Borucu U
,
Schaffitzel C
,
Berger I
Sample: SARS CoV Spike protein, Closed conformation, C3 symmetry
Fitted models: 7zh1
Deposition Authors: Toelzer C
,
Gupta K
,
Yadav SKN
,
Buzas D
,
Borucu U
,
Schaffitzel C
,
Berger I
The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Toelzer C
,
Gupta K
,
Yadav SKN
,
Hodgson L
,
Williamson MK,
Buzas D
,
Borucu U
,
Powers K
,
Stenner R
,
Vasileiou K
,
Garzoni F
,
Fitzgerald D,
Payre C,
Gautam G
,
Lambeau G
,
Davidson AD
,
Verkade P
,
Frank M
,
Berger I
,
Schaffitzel C
(2022) Sci Adv , 8 , eadc9179 - eadc9179
,
Gupta K
,
Yadav SKN
,
Hodgson L
,
Williamson MK,
Buzas D
,
Borucu U
,
Powers K
,
Stenner R
,
Vasileiou K
,
Garzoni F
,
Fitzgerald D,
Payre C,
Gautam G
,
Lambeau G
,
Davidson AD
,
Verkade P
,
Frank M
,
Berger I
,
Schaffitzel C
(2022) Sci Adv , 8 , eadc9179 - eadc9179
Grant Support:
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/P000940/1 (United Kingdom)
- Wellcome Trust: 202904/Z/16/Z (United Kingdom)
- Wellcome Trust: 206181/Z/17/Z (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/L01386X/1 (United Kingdom)
- Wellcome Trust: 210701/Z/18/Z (United Kingdom)
- Wellcome Trust: 106115/Z/14/Z (United Kingdom)
- Biotechnology and Biological Sciences Research Council (BBSRC): BB/R000484/1 (United Kingdom)
