EMD-14666

Single-particle
3.2 Å
EMD-14666
3D View Gallery
Deposition: 29/03/2022
Map released: 18/05/2022
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14666

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7zdq summary report (pdf.gz) Map-7zdq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of Human ACE2 bound to a high-affinity SARS CoV-2 mutant

EMD-14666

Single-particle
3.2 Å
EMD-14666
3D View Gallery
Deposition: 29/03/2022
Map released: 18/05/2022
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2, Homo sapiens
Sample: Complex of Human ACE2 and SARS CoV-2 RBD
Fitted models: 7zdq

Deposition Authors: Bate N, Savva CG, Moody PCE, Brown EA, Schwabe WR, Brindle NPJ, Ball JK, Sale JE
In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding.
Bate N, Savva CG, Moody PCE, Brown EA, Evans SE, Ball JK, Schwabe JWR, Sale JE , Brindle NPJ
(2022) PLoS Pathog , 18 , e1010733 - e1010733
PUBMED: 35849637
DOI: doi:10.1371/journal.ppat.1010733
ISSN: 1553-7374
Grant Support: