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EMD-14591
CryoEM structure of SARS-CoV-2 spike monomer in complex with neutralising antibody P008_60
EMD-14591
Single-particle4.31 Å
Deposition: 24/03/2022Map released: 17/08/2022
Last modified: 16/10/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Monomeric Spike glycoprotein ectodomain from SARS-CoV-2 in complex with a neutralising antibody P008_60
Fitted models: 7zbu
Deposition Authors: Rosa A, Pye VE, Cronin N, Cherepanov P
Sample: Monomeric Spike glycoprotein ectodomain from SARS-CoV-2 in complex with a neutralising antibody P008_60
Fitted models: 7zbu
Deposition Authors: Rosa A, Pye VE, Cronin N, Cherepanov P
A neutralizing epitope on the SD1 domain of SARS-CoV-2 spike targeted following infection and vaccination.
Seow J,
Khan H ,
Rosa A,
Calvaresi V ,
Graham C,
Pickering S,
Pye VE,
Cronin NB ,
Huettner I,
Malim MH,
Politis A,
Cherepanov P ,
Doores KJ
(2022) Cell Rep , 40 , 111276 - 111276
,
Rosa A,
Calvaresi V ,
Graham C,
Pickering S,
Pye VE,
Cronin NB ,
Huettner I,
Malim MH,
Politis A,
Cherepanov P ,
Doores KJ
(2022) Cell Rep , 40 , 111276 - 111276
Grant Support:
- The Francis Crick Institute: FC001061 (United Kingdom)
- Wellcome Trust: FC001061 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): FC001061 (United Kingdom)
- Cancer Research UK: FC001061 (United Kingdom)
- Wellcome Trust: 206175/Z/17/Z (United Kingdom)