Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-14543
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-B5 nanobody complex
EMD-14543
Single-particle3.1 Å
Deposition: 16/03/2022Map released: 13/07/2022
Last modified: 13/11/2024
Sample Organism:
Lama glama,
Severe acute respiratory syndrome coronavirus 2,
Escherichia virus T4
Sample: Complex between Spike and nanobody H11-B5
Fitted models: 7z85
Deposition Authors: Weckener M
,
Naismith JH,
Vogirala VK
Sample: Complex between Spike and nanobody H11-B5
Fitted models: 7z85
Deposition Authors: Weckener M
,
Naismith JH,
Vogirala VK
Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Mikolajek H ,
Weckener M ,
Brotzakis ZF,
Huo J,
Dalietou EV ,
Le Bas A ,
Sormanni P ,
Harrison PJ,
Ward PN ,
Truong S ,
Moynie L ,
Clare DK ,
Dumoux M ,
Dormon J,
Norman C,
Hussain N ,
Vogirala V ,
Owens RJ ,
Vendruscolo M ,
Naismith JH
(2022) PNAS , 119 , e2205412119 - e2205412119
,
Weckener M ,
Brotzakis ZF,
Huo J,
Dalietou EV ,
Le Bas A ,
Sormanni P ,
Harrison PJ,
Ward PN ,
Truong S ,
Moynie L ,
Clare DK ,
Dumoux M ,
Dormon J,
Norman C,
Hussain N ,
Vogirala V ,
Owens RJ ,
Vendruscolo M ,
Naismith JH
(2022) PNAS , 119 , e2205412119 - e2205412119
Grant Support:
- Engineering and Physical Sciences Research Council: P2019-0006 (United Kingdom)
- Wellcome Trust: 100209/Z/12/Z (United Kingdom)