EMD-14525
AP2 adaptor protein recruited on the membrane in the presence of FCHO2 linker
EMD-14525
Tomography9.9 Å
Deposition: 10/03/2022Map released: 11/05/2022
Last modified: 13/12/2023
Sample Organism:
Homo sapiens,
Rattus norvegicus,
Mus musculus
Sample: Clathrin adaptor protein AP2 recruited on the membrane in the presence of interdomain linker of FCHO2
Deposition Authors: Kovtun O
,
Kaufman JGG ,
Owen DJ ,
Briggs JAG
Sample: Clathrin adaptor protein AP2 recruited on the membrane in the presence of interdomain linker of FCHO2
Deposition Authors: Kovtun O
,
Kaufman JGG ,
Owen DJ ,
Briggs JAG
FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Zaccai NR ,
Kadlecova Z ,
Dickson VK ,
Korobchevskaya K,
Kamenicky J,
Kovtun O ,
Umasankar PK ,
Wrobel AG ,
Kaufman JGG ,
Gray SR ,
Qu K ,
Evans PR,
Fritzsche M ,
Sroubek F ,
Honing S,
Briggs JAG ,
Kelly BT ,
Owen DJ ,
Traub LM
(2022) Sci Adv , 8 , eabn2018 - eabn2018
,
Kadlecova Z ,
Dickson VK ,
Korobchevskaya K,
Kamenicky J,
Kovtun O ,
Umasankar PK ,
Wrobel AG ,
Kaufman JGG ,
Gray SR ,
Qu K ,
Evans PR,
Fritzsche M ,
Sroubek F ,
Honing S,
Briggs JAG ,
Kelly BT ,
Owen DJ ,
Traub LM
(2022) Sci Adv , 8 , eabn2018 - eabn2018
Grant Support:
- Wellcome Trust: 207455/Z/17/Z (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/16 (United Kingdom)