EMD-14440
Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin.
EMD-14440
Single-particle3.15 Å
Deposition: 24/02/2022Map released: 17/08/2022
Last modified: 06/11/2024
Sample Organism:
Tetronarce californica,
synthetic construct
Sample: Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin.
Fitted models: 7z14
Deposition Authors: Nys MAEM, Zarkadas E
,
Ulens C ,
Nury H
Sample: Cryo-EM structure of Torpedo nicotinic acetylcholine receptor in complex with a short-chain neurotoxin.
Fitted models: 7z14
Deposition Authors: Nys MAEM, Zarkadas E
,
Ulens C ,
Nury H
The molecular mechanism of snake short-chain alpha-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Nys M ,
Zarkadas E ,
Brams M ,
Mehregan A ,
Kambara K ,
Kool J ,
Casewell NR ,
Bertrand D ,
Baenziger JE ,
Nury H ,
Ulens C
(2022) Nat Commun , 13 , 4543 - 4543
,
Zarkadas E ,
Brams M ,
Mehregan A ,
Kambara K ,
Kool J ,
Casewell NR ,
Bertrand D ,
Baenziger JE ,
Nury H ,
Ulens C
(2022) Nat Commun , 13 , 4543 - 4543
Grant Support:
- Research Foundation - Flanders (FWO): 12X2722N (Belgium)
- KU Leuven: C32/16/035 (Belgium)
- Wellcome Trust: 221710/Z/20/Z (United Kingdom)
- French Infrastructure for Integrated Structural Biology (FRISBI): ANR-10-INSB-05-02 (France)
- Grenoble Alliance for Integrated Structural Cell Biology (GRAL): ANR- 17-EURE-0003 (France)
- European Research Council (ERC): 637733 Pentabrain (European Union)