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EMD-14250
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment
EMD-14250
Single-particle2.9 Å
Deposition: 08/02/2022Map released: 20/04/2022
Last modified: 23/10/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment
Fitted models: 7r40
Deposition Authors: Hurdiss DL
,
Drulyte I
Sample: SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment
Fitted models: 7r40
Deposition Authors: Hurdiss DL
,
Drulyte I
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.
Du W ,
Hurdiss DL ,
Drabek D ,
Mykytyn AZ ,
Kaiser FK ,
Gonzalez-Hernandez M ,
Munoz-Santos D ,
Lamers MM ,
van Haperen R ,
Li W ,
Drulyte I ,
Wang C ,
Sola I ,
Armando F ,
Beythien G ,
Ciurkiewicz M ,
Baumgartner W ,
Guilfoyle K ,
Smits T,
van der Lee J ,
van Kuppeveld FJM ,
van Amerongen G ,
Haagmans BL ,
Enjuanes L ,
Osterhaus ADME ,
Grosveld F ,
Bosch BJ
(2022) Sci Immunol , 7 , eabp9312 - eabp9312
,
Hurdiss DL ,
Drabek D ,
Mykytyn AZ ,
Kaiser FK ,
Gonzalez-Hernandez M ,
Munoz-Santos D ,
Lamers MM ,
van Haperen R ,
Li W ,
Drulyte I ,
Wang C ,
Sola I ,
Armando F ,
Beythien G ,
Ciurkiewicz M ,
Baumgartner W ,
Guilfoyle K ,
Smits T,
van der Lee J ,
van Kuppeveld FJM ,
van Amerongen G ,
Haagmans BL ,
Enjuanes L ,
Osterhaus ADME ,
Grosveld F ,
Bosch BJ
(2022) Sci Immunol , 7 , eabp9312 - eabp9312
Grant Support:
- European Commission: 101003651 (European Union)
- German Research Foundation (DFG): 398066876/GRK 2485/1 (Germany)
- German Federal Ministry for Education and Research: 01KI1723G (Germany)