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EMD-14121
Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.
EMD-14121
Single-particle2.1 Å
Deposition: 06/01/2022Map released: 18/01/2023
Last modified: 12/03/2025
Sample Organism:
Escherichia coli K-12,
Escherichia coli,
Myxococcus fulvus
Sample: Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.
Fitted models: 7qq3
Deposition Authors: Koller TO
,
Beckert B,
Wilson DN
Sample: Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.
Fitted models: 7qq3
Deposition Authors: Koller TO
,
Beckert B,
Wilson DN
The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
Koller TO ,
Scheid U,
Kosel T,
Herrmann J ,
Krug D ,
Boshoff HIM ,
Beckert B,
Evans JC ,
Schlemmer J,
Sloan B,
Weiner DM,
Via LE,
Moosa A ,
Ioerger TR,
Graf M,
Zinshteyn B,
Abdelshahid M,
Nguyen F,
Arenz S,
Gille F,
Siebke M,
Seedorf T,
Plettenburg O ,
Green R,
Warnke AL ,
Ullrich J,
Warrass R,
Barry 3rd CE ,
Warner DF ,
Mizrahi V ,
Kirschning A ,
Wilson DN ,
Muller R
(2023) J Am Chem Soc , 145 , 851 - 863
,
Scheid U,
Kosel T,
Herrmann J ,
Krug D ,
Boshoff HIM ,
Beckert B,
Evans JC ,
Schlemmer J,
Sloan B,
Weiner DM,
Via LE,
Moosa A ,
Ioerger TR,
Graf M,
Zinshteyn B,
Abdelshahid M,
Nguyen F,
Arenz S,
Gille F,
Siebke M,
Seedorf T,
Plettenburg O ,
Green R,
Warnke AL ,
Ullrich J,
Warrass R,
Barry 3rd CE ,
Warner DF ,
Mizrahi V ,
Kirschning A ,
Wilson DN ,
Muller R
(2023) J Am Chem Soc , 145 , 851 - 863