EMD-13809
Type II beta-amyloid 42 Filaments from Human Brain
EMD-13809
Helical reconstruction2.8 Å
Deposition: 01/11/2021Map released: 24/11/2021
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: beta-amyloid 42 filaments extracted from the human brain with Alzheimer's disease
Fitted models: 7q4m
Deposition Authors: Yang Y
,
Arseni D
Sample: beta-amyloid 42 filaments extracted from the human brain with Alzheimer's disease
Fitted models: 7q4m
Deposition Authors: Yang Y
,
Arseni D
Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Yang Y ,
Arseni D ,
Zhang W ,
Huang M ,
Lovestam S ,
Schweighauser M,
Kotecha A ,
Murzin AG,
Peak-Chew SY,
Macdonald J ,
Lavenir I ,
Garringer HJ ,
Gelpi E ,
Newell KL ,
Kovacs GG ,
Vidal R ,
Ghetti B ,
Ryskeldi-Falcon B ,
Scheres SHW ,
Goedert M
(2022) Science , 375 , 167 - 172
,
Arseni D ,
Zhang W ,
Huang M ,
Lovestam S ,
Schweighauser M,
Kotecha A ,
Murzin AG,
Peak-Chew SY,
Macdonald J ,
Lavenir I ,
Garringer HJ ,
Gelpi E ,
Newell KL ,
Kovacs GG ,
Vidal R ,
Ghetti B ,
Ryskeldi-Falcon B ,
Scheres SHW ,
Goedert M
(2022) Science , 375 , 167 - 172
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/25 (United States)
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United States)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): P30-AG010133 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): U01-NS110437 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): RF1-AG071177 (United States)