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EMD-13739
Tomogram of a TauRD-YFP aggregate in a TauRD-YFP expressing Hek293T cell
EMD-13739
Tomography
Deposition: 14/10/2021Map released: 31/08/2022
Last modified: 15/03/2023
Sample Organism:
Homo sapiens
Sample: Tomogram of a TauRD-YFP aggregate in a TauRD-YFP expressing Hek293T cell
Deposition Authors: Guo Q
,
Saha I,
Fernandez-Busnadiego R ,
Hartl F-U
Sample: Tomogram of a TauRD-YFP aggregate in a TauRD-YFP expressing Hek293T cell
Deposition Authors: Guo Q
,
Saha I,
Fernandez-Busnadiego R ,
Hartl F-U
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
Saha I,
Yuste-Checa P ,
Da Silva Padilha M,
Guo Q ,
Korner R,
Holthusen H ,
Trinkaus VA ,
Dudanova I ,
Fernandez-Busnadiego R ,
Baumeister W ,
Sanders DW,
Gautam S ,
Diamond MI ,
Hartl FU ,
Hipp MS
(2023) Nat Commun , 14 , 560 - 560
,
Da Silva Padilha M,
Guo Q ,
Korner R,
Holthusen H ,
Trinkaus VA ,
Dudanova I ,
Fernandez-Busnadiego R ,
Baumeister W ,
Sanders DW,
Gautam S ,
Diamond MI ,
Hartl FU ,
Hipp MS
(2023) Nat Commun , 14 , 560 - 560
Grant Support:
- European Research Council (ERC): ERC-2012-SyG_318987-ToPAG (Germany)
- German Research Foundation (DFG): EXC 2067/1-390729940 (Germany)
- German Research Foundation (DFG): (Germany)