EMD-13674

Single-particle
3.27 Å
EMD-13674
3D View Gallery
Deposition: 06/10/2021
Map released: 01/12/2021
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-13674

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7pw4 summary report (pdf.gz) Map-7pw4 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor

EMD-13674

Single-particle
3.27 Å
EMD-13674
3D View Gallery
Deposition: 06/10/2021
Map released: 01/12/2021
Last modified: 01/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: SMG1-SMG8-SMG9 kinase complex bound to a SMG1 inhibitor
Fitted models: 7pw4

Deposition Authors: Langer LM , Conti E
Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8.
Langer LM , Bonneau F , Gat Y , Conti E
(2021) eLife , 10
PUBMED: 34698635
DOI: doi:10.7554/eLife.72353
ISSN: 2050-084X
Grant Support: