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EMD-13605
Ligand-bound human Kv3.1 cryo-EM structure (Lu AG00563)
EMD-13605
Single-particle3.03 Å
Deposition: 20/09/2021Map released: 17/08/2022
Last modified: 17/07/2024
Sample Organism:
Homo sapiens
Sample: Detergent solubilized tetramer of human Kv3.1 potassium ion channel in complex with Lu AG00563
Fitted models: 7pqu
Deposition Authors: Botte M, Huber S, Bucher D
,
Klint JK,
Rodriguez D ,
Tagmose L,
Chami M ,
Cheng R,
Hennig M ,
Abdul Rhaman W
Sample: Detergent solubilized tetramer of human Kv3.1 potassium ion channel in complex with Lu AG00563
Fitted models: 7pqu
Deposition Authors: Botte M, Huber S, Bucher D
,
Klint JK,
Rodriguez D ,
Tagmose L,
Chami M ,
Cheng R,
Hennig M ,
Abdul Rhaman W
Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators.
Botte M,
Huber S,
Bucher D ,
Klint JK,
Rodriguez D ,
Tagmose L,
Chami M ,
Cheng R,
Hennig M ,
Abdul Rahman W
(2022) Pnas Nexus , 1 , pgac083 - pgac083
,
Klint JK,
Rodriguez D ,
Tagmose L,
Chami M ,
Cheng R,
Hennig M ,
Abdul Rahman W
(2022) Pnas Nexus , 1 , pgac083 - pgac083
Grant Support: