EMD-13421

Single-particle
8.0 Å
EMD-13421
3D View Gallery
Deposition: 17/08/2021
Map released: 31/08/2022
Last modified: 28/09/2022
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-13421
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Cryo-EM maps of the RET/GDF15/GFRAL complex

EMD-13421

Single-particle
8.0 Å
EMD-13421
3D View Gallery
Deposition: 17/08/2021
Map released: 31/08/2022
Last modified: 28/09/2022
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The extracellular domain complex of RET/GDF15/GFRAL

Deposition Authors: Liu YL, Muench SP, Goldman A
Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A.
Liu Y , De Castro Ribeiro O, Haapanen O , Craven GB , Sharma V , Muench SP, Goldman A
(2022) J Biol Chem , 298 , 102380 - 102380
PUBMED: 35985422
DOI: doi:10.1016/j.jbc.2022.102380
ISSN: 1083-351X
ASTM: JBCHA3