EMD-13225
Limbic-predominant neuronal inclusion body 4R tauopathy type 2 tau filament
EMD-13225
Helical reconstruction2.5 Å
Deposition: 15/07/2021Map released: 15/09/2021
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: Sarkosyl-insoluble fraction from the temporal cortex of an individual with limbic-predominant neuronal inclusion body 4R tauopathy
Fitted models: 7p6c
Deposition Authors: Shi Y
,
Zhang W
Sample: Sarkosyl-insoluble fraction from the temporal cortex of an individual with limbic-predominant neuronal inclusion body 4R tauopathy
Fitted models: 7p6c
Deposition Authors: Shi Y
,
Zhang W
Structure-based classification of tauopathies.
Shi Y ,
Zhang W ,
Yang Y ,
Murzin AG,
Falcon B,
Kotecha A ,
van Beers M,
Tarutani A ,
Kametani F ,
Garringer HJ ,
Vidal R ,
Hallinan GI ,
Lashley T ,
Saito Y ,
Murayama S,
Yoshida M,
Tanaka H ,
Kakita A,
Ikeuchi T ,
Robinson AC ,
Mann DMA,
Kovacs GG ,
Revesz T,
Ghetti B ,
Hasegawa M ,
Goedert M ,
Scheres SHW
(2021) Nature , 598 , 359 - 363
,
Zhang W ,
Yang Y ,
Murzin AG,
Falcon B,
Kotecha A ,
van Beers M,
Tarutani A ,
Kametani F ,
Garringer HJ ,
Vidal R ,
Hallinan GI ,
Lashley T ,
Saito Y ,
Murayama S,
Yoshida M,
Tanaka H ,
Kakita A,
Ikeuchi T ,
Robinson AC ,
Mann DMA,
Kovacs GG ,
Revesz T,
Ghetti B ,
Hasegawa M ,
Goedert M ,
Scheres SHW
(2021) Nature , 598 , 359 - 363
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Innovative Medicines Initiative: 116060 (European Union)
- Japan Science and Technology: JPMJCR18H3 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP20dm0207072 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP21dk0207045 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP21ek0109545 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP20ek0109392 (Japan)
- Japan Agency for Medical Research and Development (AMED): JP20ek0109391 (Japan)
- National Institutes of Health/National Institute on Aging (NIH/NIA): P30-AG010133 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): UO1-NS110437 (United States)
- National Institutes of Health/National Institute on Aging (NIH/NIA): RF1-AG071177 (United States)