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EMD-13097
human DEPTOR in a complex with mutant human mTORC1 A1459P
EMD-13097
Single-particle4.7 Å
Deposition: 18/06/2021Map released: 08/09/2021
Last modified: 17/07/2024
Sample Organism:
Homo sapiens
Sample: COMPLEX OF HUMAN MUTANT MTORC1 A1459P WITH THE INHIBITORY PROTEIN DEPTOR
Fitted models: 7owg
Deposition Authors: Heimhalt M
,
Berndt A
Sample: COMPLEX OF HUMAN MUTANT MTORC1 A1459P WITH THE INHIBITORY PROTEIN DEPTOR
Fitted models: 7owg
Deposition Authors: Heimhalt M
,
Berndt A
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
Heimhalt M
,
Berndt A,
Wagstaff J,
Anandapadamanaban M
,
Perisic O,
Maslen S,
McLaughlin S,
Yu CW
,
Masson GR
,
Boland A
,
Ni X,
Yamashita K
,
Murshudov GN,
Skehel M,
Freund SM,
Williams RL
(2021) eLife , 10
,
Berndt A,
Wagstaff J,
Anandapadamanaban M
,
Perisic O,
Maslen S,
McLaughlin S,
Yu CW
,
Masson GR
,
Boland A
,
Ni X,
Yamashita K
,
Murshudov GN,
Skehel M,
Freund SM,
Williams RL
(2021) eLife , 10
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_U105184308 (United Kingdom)
- Cancer Research UK: C14801/A21211 (United Kingdom)
- European Molecular Biology Organization (EMBO): EMBO ALTF 603-2019 (United Kingdom)
