EMD-13077

Single-particle
3.5 Å
EMD-13077
3D View Gallery
Deposition: 11/06/2021
Map released: 18/08/2021
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-13077

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7ouh summary report (pdf.gz) Map-7ouh FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor bictegravir

EMD-13077

Single-particle
3.5 Å
EMD-13077
3D View Gallery
Deposition: 11/06/2021
Map released: 18/08/2021
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Simian T-lymphotropic virus 1, Homo sapiens
Sample: Complex of STLV-1 MarB43 integrase with nascent viral DNA, the human PP2A B56 subunit and the drug inhibitor bictegravir
Fitted models: 7ouh

Deposition Authors: Barski MS , Ballandras-Colas A
Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
Barski MS , Vanzo T , Zhao XZ , Smith SJ , Ballandras-Colas A , Cronin NB , Pye VE , Hughes SH , Burke Jr TR , Cherepanov P , Maertens GN
(2021) Nat Commun , 12 , 4996 - 4996
PUBMED: 34404793
DOI: doi:10.1038/s41467-021-25284-1
ISSN: 2041-1723