Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-13046

Single-particle
2.76 Å
EMD-13046
3D View Gallery
Deposition: 07/06/2021
Map released: 23/02/2022
Last modified: 25/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-13046
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7os2 summary report (pdf.gz) Map and 7os2 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78

EMD-13046

Single-particle
2.76 Å
EMD-13046
3D View Gallery
Deposition: 07/06/2021
Map released: 23/02/2022
Last modified: 25/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Trimeric complex of Brr2, the Jab1/MPN domain of Prp8 and a N-terminal fragment of C9ORF78
Fitted models: 7os2

Deposition Authors: Bergfort A, Hilal T
The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Bergfort A, Hilal T, Kuropka B , Ilik IA, Weber G , Aktas T , Freund C, Wahl MC
(2022) Nucleic Acids Res , 50 , 2938 - 2958
PUBMED: 35188580
DOI: doi:10.1093/nar/gkac087
ISSN: 1362-4962
ASTM: NARHAD
Grant Support: