EMD-12952

Single-particle
3.4 Å
EMD-12952
3D View Gallery
Deposition: 16/05/2021
Map released: 21/07/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12952

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7oji summary report (pdf.gz) Map-7oji FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

ABCG2 topotecan turnover-2 state

EMD-12952

Single-particle
3.4 Å
EMD-12952
3D View Gallery
Deposition: 16/05/2021
Map released: 21/07/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ABCG2 in complex with topotecan under turnover condition
Fitted models: 7oji

Deposition Authors: Yu Q , Ni D
Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism.
Yu Q , Ni D, Kowal J , Manolaridis I , Jackson SM, Stahlberg H , Locher KP
(2021) Nat Commun , 12 , 4376 - 4376
PUBMED: 34282134
DOI: doi:10.1038/s41467-021-24651-2
ISSN: 2041-1723
Grant Support: