Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-12755

Single-particle
4.3 Å
EMD-12755 Deposition: 13/04/2021
Map released: 13/04/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12755

(h-alpha2M)4 plasmin-activated II state

EMD-12755

Single-particle
4.3 Å
EMD-12755 Deposition: 13/04/2021
Map released: 13/04/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human alpha-2-macroglobulin plasmin-activated II state
Fitted models: 7o7s

Deposition Authors: Luque D , Goulas T
Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin.
Luque D , Goulas T , Mata CP , Mendes SR , Gomis-Ruth FX , Caston JR
(2022) PNAS , 119 , e2200102119 - e2200102119
PUBMED: 35500114
DOI: doi:10.1073/pnas.2200102119
ISSN: 1091-6490
ASTM: PNASA6