EMD-12585
Trimeric SARS-CoV-2 spike ectodomain in complex with biliverdin (closed conformation)
EMD-12585
Single-particle3.36 Å
Deposition: 09/03/2021Map released: 28/04/2021
Last modified: 09/06/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: Ectodomain of spike glycoprotein from SARS-CoV-2 expressed in HEK cells and purified. Data were collected in the presence of excess biliverdin.
Fitted models: 7nt9
Deposition Authors: Rosa A, Pye VE, Nans A, Cherepanov P
Sample: Ectodomain of spike glycoprotein from SARS-CoV-2 expressed in HEK cells and purified. Data were collected in the presence of excess biliverdin.
Fitted models: 7nt9
Deposition Authors: Rosa A, Pye VE, Nans A, Cherepanov P
SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Rosa A 
,
Pye VE ,
Graham C,
Muir L ,
Seow J ,
Ng KW ,
Cook NJ ,
Rees-Spear C ,
Parker E,
Dos Santos MS ,
Rosadas C ,
Susana A ,
Rhys H,
Nans A ,
Masino L ,
Roustan C ,
Christodoulou E ,
Ulferts R ,
Wrobel AG ,
Short CE ,
Fertleman M ,
Sanders RW ,
Heaney J,
Spyer M ,
Kjaer S ,
Riddell A ,
Malim MH ,
Beale R ,
MacRae JI ,
Taylor GP ,
Nastouli E,
van Gils MJ ,
Rosenthal PB ,
Pizzato M ,
McClure MO,
Tedder RS ,
Kassiotis G ,
McCoy LE ,
Doores KJ ,
Cherepanov P
(2021) Sci Adv , 7
,
Pye VE ,
Graham C,
Muir L ,
Seow J ,
Ng KW ,
Cook NJ ,
Rees-Spear C ,
Parker E,
Dos Santos MS ,
Rosadas C ,
Susana A ,
Rhys H,
Nans A ,
Masino L ,
Roustan C ,
Christodoulou E ,
Ulferts R ,
Wrobel AG ,
Short CE ,
Fertleman M ,
Sanders RW ,
Heaney J,
Spyer M ,
Kjaer S ,
Riddell A ,
Malim MH ,
Beale R ,
MacRae JI ,
Taylor GP ,
Nastouli E,
van Gils MJ ,
Rosenthal PB ,
Pizzato M ,
McClure MO,
Tedder RS ,
Kassiotis G ,
McCoy LE ,
Doores KJ ,
Cherepanov P
(2021) Sci Adv , 7