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EMD-12564
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
EMD-12564
Single-particle3.3 Å
Deposition: 05/03/2021Map released: 05/05/2021
Last modified: 02/07/2025
Sample Organism:
Homo sapiens
Sample: SRS module of human CTLH complex comprising RANBP9, TWA1, ARMC8 and hGid4
Fitted models: 7nsc
Deposition Authors: Chrustowicz J
,
Sherpa D
,
Prabu JR
,
Schulman BA
Sample: SRS module of human CTLH complex comprising RANBP9, TWA1, ARMC8 and hGid4
Fitted models: 7nsc
Deposition Authors: Chrustowicz J
,
Sherpa D
,
Prabu JR
,
Schulman BA
GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Sherpa D
,
Chrustowicz J
,
Qiao S
,
Langlois CR
,
Hehl LA,
Gottemukkala KV
,
Hansen FM
,
Karayel O,
von Gronau S,
Prabu JR
,
Mann M,
Alpi AF,
Schulman BA
(2021) Mol Cell , 81 , 2445
,
Chrustowicz J
,
Qiao S
,
Langlois CR
,
Hehl LA,
Gottemukkala KV
,
Hansen FM
,
Karayel O,
von Gronau S,
Prabu JR
,
Mann M,
Alpi AF,
Schulman BA
(2021) Mol Cell , 81 , 2445
Grant Support:
- European Research Council (ERC): 789016-NEDD8Activate (Germany)
- German Research Foundation (DFG): SCHU 3196/1-1 (Germany)
