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EMD-12528
Cryo-EM structure of the mammalian peptide transporter PepT2
EMD-12528
Single-particle3.5 Å
Deposition: 01/03/2021Map released: 07/07/2021
Last modified: 02/07/2025
Sample Organism:
Rattus norvegicus,
Lama glama
Sample: Complex of the mammalian peptide transporter PepT2 with nanobody
Fitted models: 7nqk
Deposition Authors: Parker JL
,
Deme JC
,
Lea SM
,
Newstead S
Sample: Complex of the mammalian peptide transporter PepT2 with nanobody
Fitted models: 7nqk
Deposition Authors: Parker JL
,
Deme JC
,
Lea SM
,
Newstead S
Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.
Parker JL
,
Deme JC
,
Wu Z
,
Kuteyi G,
Huo J
,
Owens RJ
,
Biggin PC
,
Lea SM
,
Newstead S
(2021) Sci Adv , 7
,
Deme JC
,
Wu Z
,
Kuteyi G,
Huo J
,
Owens RJ
,
Biggin PC
,
Lea SM
,
Newstead S
(2021) Sci Adv , 7
Grant Support:
- Wellcome Trust: 201536 (United Kingdom)
- Wolfson Foundation: WL16005 (United Kingdom)
- Engineering and Physical Sciences Research Council: EP/L000253/1 (United Kingdom)
- Wellcome Trust: 209194 (United Kingdom)
- Wellcome Trust: 100298 (United Kingdom)
- Wellcome Trust: 219531 (United Kingdom)
- Wellcome Trust: 215519 (United Kingdom)
- Wellcome Trust: 219531 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MR/M011984/1 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MR/S021043/1 (United Kingdom)
- Wellcome Trust: 203741 (United Kingdom)
