EMD-12513
cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture
EMD-12513
Single-particle3.3 Å
Deposition: 26/02/2021Map released: 11/08/2021
Last modified: 09/07/2025
Sample Organism:
Oryctolagus cuniculus
Sample: HCN4
Fitted models: 7np4
Deposition Authors: Giese H, Saponaro A
Sample: HCN4
Fitted models: 7np4
Deposition Authors: Giese H, Saponaro A
Gating movements and ion permeation in HCN4 pacemaker channels.
Saponaro A ,
Bauer D ,
Giese MH,
Swuec P,
Porro A,
Gasparri F,
Sharifzadeh AS,
Chaves-Sanjuan A ,
Alberio L ,
Parisi G ,
Cerutti G ,
Clarke OB,
Hamacher K,
Colecraft HM,
Mancia F,
Hendrickson WA,
Siegelbaum SA,
DiFrancesco D,
Bolognesi M,
Thiel G ,
Santoro B,
Moroni A
(2021) Mol Cell , 81 , 2929 - 2943.e6
,
Bauer D ,
Giese MH,
Swuec P,
Porro A,
Gasparri F,
Sharifzadeh AS,
Chaves-Sanjuan A ,
Alberio L ,
Parisi G ,
Cerutti G ,
Clarke OB,
Hamacher K,
Colecraft HM,
Mancia F,
Hendrickson WA,
Siegelbaum SA,
DiFrancesco D,
Bolognesi M,
Thiel G ,
Santoro B,
Moroni A
(2021) Mol Cell , 81 , 2929 - 2943.e6
Grant Support:
- Leducq Foundation: TNE19CVD03 (United States)
- Fondazione CARIPLO: 2018-0231 (Italy)
- European Research Council (ERC): ERC Advanced grant noMAGIC 695078 (European Union)
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): NIH grants R01-NS109366 (United States)
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): P41-GM116799 (United States)
- National Institutes of Health/National Center for Research Resources (NIH/NCRR): R01-GM107462 via Type a message (United States)