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EMD-12451
Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
EMD-12451
Single-particle2.5 Å
Deposition: 19/02/2021Map released: 22/09/2021
Last modified: 23/10/2024
Sample Organism:
Mycobacterium tuberculosis H37Rv
Sample: Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
Fitted models: 7nkz
Deposition Authors: Safarian S
,
Wu D
Sample: Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
Fitted models: 7nkz
Deposition Authors: Safarian S
,
Wu D
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Safarian S ,
Opel-Reading HK,
Wu D,
Mehdipour AR ,
Hards K,
Harold LK ,
Radloff M ,
Stewart I,
Welsch S ,
Hummer G ,
Cook GM ,
Krause KL ,
Michel H
(2021) Nat Commun , 12 , 5236 - 5236
,
Opel-Reading HK,
Wu D,
Mehdipour AR ,
Hards K,
Harold LK ,
Radloff M ,
Stewart I,
Welsch S ,
Hummer G ,
Cook GM ,
Krause KL ,
Michel H
(2021) Nat Commun , 12 , 5236 - 5236
Grant Support:
- German Research Foundation (DFG): (Germany)
- Max Planck Society: Nobel Laureate Fellowship (Germany)
- Marsden Fund: (New Zealand)
- Royal Society of New Zealand: Catalyst grant (New Zealand)