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EMD-12332
VgaA-LC, an antibiotic resistance ABCF, in complex with 70S ribosome from Staphylococcus aureus
EMD-12332
Single-particle3.1 Å
Deposition: 10/02/2021Map released: 05/05/2021
Last modified: 01/05/2024
Sample Organism:
Staphylococcus aureus subsp. aureus NCTC 8325,
Staphylococcus haemolyticus
Sample: VgaA-LC in complex with 70S ribosome, mRNA, and distorted P-tRNA from Staphylococcus aureus
Fitted models: 7nhl
Deposition Authors: Crowe-McAuliffe C
,
Murina V
Sample: VgaA-LC in complex with 70S ribosome, mRNA, and distorted P-tRNA from Staphylococcus aureus
Fitted models: 7nhl
Deposition Authors: Crowe-McAuliffe C
,
Murina V
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Crowe-McAuliffe C
,
Murina V
,
Turnbull KJ
,
Kasari M,
Mohamad M
,
Polte C,
Takada H
,
Vaitkevicius K,
Johansson J
,
Ignatova Z
,
Atkinson GC
,
O'Neill AJ,
Hauryliuk V
,
Wilson DN
(2021) Nat Commun , 12 , 3577 - 3577
,
Murina V
,
Turnbull KJ
,
Kasari M,
Mohamad M
,
Polte C,
Takada H
,
Vaitkevicius K,
Johansson J
,
Ignatova Z
,
Atkinson GC
,
O'Neill AJ,
Hauryliuk V
,
Wilson DN
(2021) Nat Commun , 12 , 3577 - 3577
Grant Support:
- German Research Foundation (DFG): WI3285/8-1 (Germany)
- Swedish Research Council: 2017-03783 (Sweden)
- Swedish Research Council: 2019-01085 (Sweden)
- European Regional Development Fund: 2014-2020.4.01.15-0013 (Sweden)
- Estonian Research Council: PRG335 (Estonia)
- Swedish Research Council: 2018-00956 (Sweden)
