Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-12331
LsaA, an antibiotic resistance ABCF, in complex with 70S ribosome from Enterococcus faecalis
EMD-12331
Single-particle2.9 Å
Deposition: 10/02/2021Map released: 05/05/2021
Last modified: 10/07/2024
Sample Organism:
Enterococcus faecalis
Sample: LsaA-in complex with 70S ribosome, mRNA, and tRNA
Fitted models: 7nhk
Deposition Authors: Crowe-McAuliffe C
,
Kasari M
Sample: LsaA-in complex with 70S ribosome, mRNA, and tRNA
Fitted models: 7nhk
Deposition Authors: Crowe-McAuliffe C
,
Kasari M
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Crowe-McAuliffe C
,
Murina V
,
Turnbull KJ
,
Kasari M,
Mohamad M
,
Polte C,
Takada H
,
Vaitkevicius K,
Johansson J
,
Ignatova Z
,
Atkinson GC
,
O'Neill AJ,
Hauryliuk V
,
Wilson DN
(2021) Nat Commun , 12 , 3577 - 3577
,
Murina V
,
Turnbull KJ
,
Kasari M,
Mohamad M
,
Polte C,
Takada H
,
Vaitkevicius K,
Johansson J
,
Ignatova Z
,
Atkinson GC
,
O'Neill AJ,
Hauryliuk V
,
Wilson DN
(2021) Nat Commun , 12 , 3577 - 3577
Grant Support:
- German Research Foundation (DFG): WI3285/8-1 (Germany)
- Swedish Research Council: 2017-03783 (Sweden)
- Swedish Research Council: 2019-01085 (Sweden)
- European Regional Development Fund: 2014-2020.4.01.15-0013 (Sweden)
- Estonian Research Council: PRG335 (Estonia)
- Swedish Research Council: 2018-00956 (Sweden)
