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EMD-12286
Cryo-EM structure of the ternary Netrin 1-Neogenin 1-Repulsive Guidance Molecule B complex
EMD-12286
Single-particle5.98 Å
Deposition: 01/02/2021Map released: 31/03/2021
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Cryo-EM structure of the ternary Netrin 1-Neogenin 1-Repulsive Guidance Molecule B complex
Fitted models: 7ndg
Deposition Authors: Robinson RA
,
Griffiths SC
Sample: Cryo-EM structure of the ternary Netrin 1-Neogenin 1-Repulsive Guidance Molecule B complex
Fitted models: 7ndg
Deposition Authors: Robinson RA
,
Griffiths SC
Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Robinson RA
,
Griffiths SC,
van de Haar LL
,
Malinauskas T
,
van Battum EY,
Zelina P,
Schwab RA,
Karia D,
Malinauskaite L
,
Brignani S,
van den Munkhof MH,
Dudukcu O
,
De Ruiter AA,
Van den Heuvel DMA,
Bishop B,
Elegheert J
,
Aricescu AR
,
Pasterkamp RJ,
Siebold C
(2021) Cell , 184 , 2103
,
Griffiths SC,
van de Haar LL
,
Malinauskas T
,
van Battum EY,
Zelina P,
Schwab RA,
Karia D,
Malinauskaite L
,
Brignani S,
van den Munkhof MH,
Dudukcu O
,
De Ruiter AA,
Van den Heuvel DMA,
Bishop B,
Elegheert J
,
Aricescu AR
,
Pasterkamp RJ,
Siebold C
(2021) Cell , 184 , 2103
Grant Support:
- Cancer Research UK: C20724/A14414 (United Kingdom)
- Cancer Research UK: C20724/A26752 (United Kingdom)
- European Research Council (ERC): 647278 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MR/L017776/1 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MR/L009609/1 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_UP_1201/15 (United Kingdom)
- Wellcome Trust: 099675/Z/12/Z (United Kingdom)
- Wellcome Trust: 090532/Z/09/Z (United Kingdom)
- Netherlands Organisation for Scientific Research (NWO): ALW-VICI (Netherlands)
- H2020 Marie Curie Actions of the European Commission: 289581 (Netherlands)
