EMD-12158

Single-particle
2.85 Å
EMD-12158
3D View Gallery
Deposition: 24/12/2020
Map released: 12/01/2022
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12158

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7bes summary report (pdf.gz) Map-7bes FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

CryoEM structure of Mycobacterium tuberculosis UMP Kinase (UMPK) in complex with UDP and UTP

EMD-12158

Single-particle
2.85 Å
EMD-12158
3D View Gallery
Deposition: 24/12/2020
Map released: 12/01/2022
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mycobacterium tuberculosis
Sample: UMPK-UDP-UTP
Fitted models: 7bes

Deposition Authors: Bous J , Trapani S
Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Walter P, Mechaly A , Bous J , Haouz A , England P, Lai-Kee-Him J , Ancelin A, Hoos S, Baron B, Trapani S , Bron P , Labesse G, Munier-Lehmann H
(2022) FEBS J , 289 , 4869 - 4887
PUBMED: 35152545
DOI: doi:10.1111/febs.16393
ISSN: 1742-464X