EMD-12142

Single-particle
3.43 Å
EMD-12142
3D View Gallery
Deposition: 21/12/2020
Map released: 22/09/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12142

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7bcq summary report (pdf.gz) Map-7bcq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

ASCT2 in the presence of the inhibitor Lc-BPE in the outward-open conformation.

EMD-12142

Single-particle
3.43 Å
EMD-12142
3D View Gallery
Deposition: 21/12/2020
Map released: 22/09/2021
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ASCT2 in the presence of the inhibitor Lc-BPE in the outward-open conformation.
Fitted models: 7bcq

Deposition Authors: Garibsingh RA , Ndaru E
Rational design of ASCT2 inhibitors using an integrated experimental-computational approach.
Garibsingh RA , Ndaru E , Garaeva AA , Shi Y, Zielewicz L, Zakrepine P, Bonomi M , Slotboom DJ , Paulino C , Grewer C , Schlessinger A
(2021) PNAS , 118
PUBMED: 34507995
DOI: doi:10.1073/pnas.2104093118
ISSN: 1091-6490
ASTM: PNASA6