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EMD-12141

Single-particle
3.3 Å
EMD-12141
3D View Gallery
Deposition: 18/12/2020
Map released: 12/05/2021
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12141
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7bc7 summary report (pdf.gz) Map and 7bc7 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed

EMD-12141

Single-particle
3.3 Å
EMD-12141
3D View Gallery
Deposition: 18/12/2020
Map released: 12/05/2021
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Gallus gallus, Lama glama
Sample: Complex of the proton coupled folate transporter at pH 6.0 bound to pemetrexed
Fitted models: 7bc7

Deposition Authors: Parker JL , Deme JC , Lea SM , Newstead S
Structural basis of antifolate recognition and transport by PCFT.
Parker JL , Deme JC , Kuteyi G, Wu Z , Huo J, Goldman ID, Owens RJ , Biggin PC , Lea SM , Newstead S
(2021) Nature , 595 , 130 - 134
PUBMED: 34040256
DOI: doi:10.1038/s41586-021-03579-z
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: