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EMD-12083
Cryo-EM map of the SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68 in a 1up/1up-out/1down conformation.
EMD-12083
Single-particle3.32 Å
Deposition: 10/12/2020Map released: 23/12/2020
Last modified: 23/12/2020
Sample Organism:
synthetic construct,
Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68
Deposition Authors: Walter JD, Hutter CAJ, Garaeva AA, Scherer M, Zimmermann I, Wyss M, Rheinberger J, Ruedin Y, Earp JC, Egloff P, Sorgenfrei M, Huerlimann LM, Gonda I, Meier G, Remm S, Thavarasah S, Zimmer G, Slotboom DJ, Paulino C, Plattet P, Seeger MA
Sample: SARS-CoV-2 spike protein in complex with sybody#15 and sybody#68
Deposition Authors: Walter JD, Hutter CAJ, Garaeva AA, Scherer M, Zimmermann I, Wyss M, Rheinberger J, Ruedin Y, Earp JC, Egloff P, Sorgenfrei M, Huerlimann LM, Gonda I, Meier G, Remm S, Thavarasah S, Zimmer G, Slotboom DJ, Paulino C, Plattet P, Seeger MA
Highly potent bispecific sybodies neutralize SARS-CoV-2
Walter JD,
Hutter CAJ,
Garaeva AA,
Scherer M,
Zimmermann I,
Wyss M,
Rheinberger J,
Ruedin Y,
Earp JC,
Egloff P,
Sorgenfrei M,
Huerlimann LM,
Gonda I,
Meier G,
Remm S,
Thavarasah S,
Zimmer G,
Slotboom DJ,
Paulino C,
Plattet P,
Seeger MA
(2020) bioRxiv
(2020) bioRxiv
Grant Support:
- Netherlands Organisation for Scientific Research (NWO): 722.017.001 (Netherlands)
- Swiss National Science Foundation: 4078P0_198314 (Switzerland)
- Netherlands Organisation for Scientific Research (NWO): 740.018.016 (Netherlands)