EMD-12042

Single-particle
2.5 Å
EMD-12042
3D View Gallery
Deposition: 05/12/2020
Map released: 10/02/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12042

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7b5o summary report (pdf.gz) Map-7b5o FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the human CAK bound to ICEC0942 at 2.5 Angstroms resolution

EMD-12042

Single-particle
2.5 Å
EMD-12042
3D View Gallery
Deposition: 05/12/2020
Map released: 10/02/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: CDK-activating kinase (CAK) in complex with ICEC0942
Fitted models: 7b5o

Deposition Authors: Greber BJ , Remis J
2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
Greber BJ , Remis J, Ali S , Nogales E
(2021) Biophys J , 120 , 677 - 686
PUBMED: 33476598
DOI: doi:10.1016/j.bpj.2020.12.030
ISSN: 1542-0086
ASTM: BIOJAU