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EMD-12041

Single-particle
3.6 Å
EMD-12041
3D View Gallery
Deposition: 05/12/2020
Map released: 10/02/2021
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12041
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7b5n summary report (pdf.gz) Map and 7b5n FULL report (pdf.gz)
EMICSS annotations (xml)

Focused map-catalytic side. Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.

EMD-12041

Single-particle
3.6 Å
EMD-12041
3D View Gallery
Deposition: 05/12/2020
Map released: 10/02/2021
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 composite map.
Fitted models: 7b5n

Deposition Authors: Horn-Ghetko D , Prabu JR , Schulman BA
Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Horn-Ghetko D , Krist DT, Prabu JR , Baek K , Mulder MPC , Klugel M, Scott DC, Ovaa H , Kleiger G, Schulman BA
(2021) Nature , 590 , 671 - 676
PUBMED: 33536622
DOI: doi:10.1038/s41586-021-03197-9
ISSN: 1476-4687
ASTM: NATUAS