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EMD-11997
Structure of a nanoparticle for a COVID-19 vaccine candidate
EMD-11997
Single-particle3.7 Å
Deposition: 01/12/2020Map released: 13/01/2021
Last modified: 13/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Sample: RBD-Spycatcher-mi3
Fitted models: 7b3y
Deposition Authors: Duyvesteyn HME
,
Stuart DI
Sample: RBD-Spycatcher-mi3
Fitted models: 7b3y
Deposition Authors: Duyvesteyn HME
,
Stuart DI
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.
Tan TK ,
Rijal P,
Rahikainen R ,
Keeble AH ,
Schimanski L,
Hussain S ,
Harvey R,
Hayes JWP,
Edwards JC,
McLean RK ,
Martini V,
Pedrera M ,
Thakur N ,
Conceicao C,
Dietrich I ,
Shelton H ,
Ludi A,
Wilsden G,
Browning C,
Zagrajek AK,
Bialy D,
Bhat S ,
Stevenson-Leggett P,
Hollinghurst P,
Tully M ,
Moffat K ,
Chiu C,
Waters R,
Gray A,
Azhar M,
Mioulet V,
Newman J ,
Asfor AS,
Burman A,
Crossley S ,
Hammond JA,
Tchilian E ,
Charleston B,
Bailey D,
Tuthill TJ ,
Graham SP ,
Duyvesteyn HME ,
Malinauskas T ,
Huo J,
Tree JA ,
Buttigieg KR,
Owens RJ ,
Carroll MW,
Daniels RS ,
McCauley JW ,
Stuart DI ,
Huang KA,
Howarth M ,
Townsend AR
(2021) Nat Commun , 12 , 542 - 542
,
Rijal P,
Rahikainen R ,
Keeble AH ,
Schimanski L,
Hussain S ,
Harvey R,
Hayes JWP,
Edwards JC,
McLean RK ,
Martini V,
Pedrera M ,
Thakur N ,
Conceicao C,
Dietrich I ,
Shelton H ,
Ludi A,
Wilsden G,
Browning C,
Zagrajek AK,
Bialy D,
Bhat S ,
Stevenson-Leggett P,
Hollinghurst P,
Tully M ,
Moffat K ,
Chiu C,
Waters R,
Gray A,
Azhar M,
Mioulet V,
Newman J ,
Asfor AS,
Burman A,
Crossley S ,
Hammond JA,
Tchilian E ,
Charleston B,
Bailey D,
Tuthill TJ ,
Graham SP ,
Duyvesteyn HME ,
Malinauskas T ,
Huo J,
Tree JA ,
Buttigieg KR,
Owens RJ ,
Carroll MW,
Daniels RS ,
McCauley JW ,
Stuart DI ,
Huang KA,
Howarth M ,
Townsend AR
(2021) Nat Commun , 12 , 542 - 542
Grant Support:
- Chinese Academy of Sciences: 2018-I2M-2-002 (United Kingdom)