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EMD-11994

Single-particle
3.4 Å
EMD-11994
3D View Gallery
Deposition: 30/11/2020
Map released: 23/12/2020
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11994
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7b3c summary report (pdf.gz) Map and 7b3c FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -4 (structure 2)

EMD-11994

Single-particle
3.4 Å
EMD-11994
3D View Gallery
Deposition: 30/11/2020
Map released: 23/12/2020
Last modified: 10/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 RNA-dependent RNA polymerase complex (nsp12, nsp7, nsp8) with elongation scaffold containing remdesivir at position -4.
Fitted models: 7b3c

Deposition Authors: Kokic G , Hillen HS
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir.
Kokic G , Hillen HS , Tegunov D , Dienemann C , Seitz F, Schmitzova J , Farnung L , Siewert A, Hobartner C , Cramer P
(2021) Nat Commun , 12 , 279 - 279
PUBMED: 33436624
DOI: doi:10.1038/s41467-020-20542-0
ISSN: 2041-1723